Table 1 Validity of remission by approximation in major depression
From: Clinical validity of a population database definition of remission in patients with major depression
Validation Method | Reference Criteria | |
|---|---|---|
Remission by Approximation | Clinical Histories | |
N = 133 | Positive | Negative |
Positive | 74 | 5 |
Negative | 6 | 48 |
Statistics | Value (%) | 95% CI |
Validity of the measurement | ||
Sensitivity | 92.5 | 88.0 - 96.9 |
Specificity | 90.6 | 85.6 - 95.6 |
Positive predictive value | 93.7 | 89.6 - 97.8 |
Negative predictive value | 88.9 | 83.6 - 94.2 |
False positives | 7.5 | 3.0 - 11.9 |
False negatives | 9.4 | 4.4 - 14.4 |
Reliability | ||
Cronbach's alpha | 90.6 | 85.6 - 95.6 |
Area under the curve | 91.2 | 86.5 - 96.1 |
Concordance | ||
McNemar test | 58.1 | 49.7 - 66.5 |
Pearson correlation | 82.8 | 73.1 - 92.5 |
Weighted kappa (Cohen) | 82.8 | 73.1 - 92.6 |
Clinical utility | ||
Positive Probability Ratio | 9.8 | --- |
Negative Probability Ratio | 0.1 | --- |