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Table 7 Cost effectiveness analysis of selected interventions

From: Estimation of the burden of cardiovascular disease attributable to modifiable risk factors and cost-effectiveness analysis of preventative interventions to reduce this burden in Argentina

Intervention Total costs Net Total costs * DALY saved † Percent of DALY saved ICER per DALY saved‡
  I$ I$ DALY (95%CI) % (95%CI) I$ (95%CI)
Reducing salt in bread 193,576.23 -946,580.87 672.80 0.11% -1,406.93
  (-) (-) (-) (-) (-)
Treatment targeted to persons with an absolute risk above 20% in 10 years (polypill strategy 23,489,613.55 -2,979,727.10 12,108.15 1.98% -246.45
  (22,002,839.35 - 24,877,996.13) (-3,663,248.39- -2,301,924.52) (11,396.45- 12,752.71) (1.86% - 2.09%) (-307.74 - -189.68)
Pharmacological therapy for high blood pressure 62,251,491.82 41,014,269.81 14,100.16 2.31% 2,908.86
  (61,201,512.65 - 63,303,292.70) (40,070,763.64 - 42,021,481.43) (13,919.53 - 14,275.31) (2.28% - 2.33%) (2,841.81 - 2,977.48)
Mass Media Campaign to promote tobacco cessation 3,164,785.75 2,053,674.53 644.73 0.11% 3,186.71
  (-) (2,012,812.78 - 2,090,361.57) (624.52 - 666.90) (0.10% - 0.11%) (3,024.42 - 3,337.92)
Pharmacological therapy of high cholesterol 92,751,189.47 81,762,199.07 5,666.16 0.93% 14,431.46
  (90,559,448.95 - 94,981,610.94) (79,775,242.39 - 83,805,632.99) (5,507.87 - 5,824.03) (0.90% - 0.95%) (14,077.55 - 14,809.92)
Therapy with Bupropion for 51,778,301.95 50,318,932.00 846.80 0.14% 59,433.02
tobacco cessation (50,792,163.89 - 52,752,733.57) (49,372,843.67 - 51,286,965.18) (820.26 - 875.93) (0.13% - 0.14%) (57,819.14 - 60,906.25)
  1. 95%CI: 95% confidence interval, I$: international dollars - PPP conversion rate (2007) 1.55 Argentinean peso = 1 I$, DALY: disability adjusted life years, ICER: incremental cost-effectiveness ratio. The ICERs express the results of 1,000 iterations.
  2. * Net Total costs are calculated as Total costs minus the corresponding averted event costs. All costs are measured in 2007 International dollars (I$).
  3. ‡ Derived from bootstrapping techniques.