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Table 6 Proportional Burden of Disease and costs attributable to each cardiovascular risk factor potentially modifiable

From: Estimation of the burden of cardiovascular disease attributable to modifiable risk factors and cost-effectiveness analysis of preventative interventions to reduce this burden in Argentina

  

Population-attributable Fraction% (95%CI)

Both sexes

Tobacco use

Overweight and Obesity

High Blood pressure

High cholesterol

High glycemia

Physical inactivity

Total AMI events (both fatal and non-fatal)

22.5 (22.2 - 22.8)

20.9 (20.4 - 21.3)

38.5 (37.9 - 39.1)

25.1 (24.4 - 25.8)

13.9 (13.2 - 14.5)

20.9 (20.6 - 21.2)

Total non-infarction events (both fatal and non-fatal)

18.5 (18.1 - 18.8)

18.6 (18.2 - 19.0)

40.9 (40.1 - 41.5)

26.2 (25.2 - 27.0)

14.8 (14.0 - 15.6)

21.6 (21.2 - 22.0)

Total stroke events (both fatal and non-fatal)

10.8 (10.5 - 11.2)

11.7 (11.3 - 12.0)

32.7 (32.0 - 33.3)

5.8 (5.6 - 6.1)

13.2 (12.3 - 14.0)

13.0 (12.7 - 13.3)

Total events (both fatal and non-fatal)

16.9 (16.5 - 17.2)

16.7 (16.3 - 17.0)

37.0 (36.3 - 37.5)

18.0 (17.4 - 18.5)

13.9 (13.1 - 14.6)

18.1 (17.7 - 18.3)

Total costs*

17.3 (17.0 - 17.6)

17.1 (16.7 - 17.4)

37.3 (36.6 - 37.9)

18.9 (18.3 - 19.5)

13.9 (13.2 - 14.7)

18.4 (18.1 - 18.7)

Total DALY†

16.1 (15.7 - 16.4)

13.8 (13.5 - 14.0)

36.6 (36.1 - 37.0)

13.4 (13.0 - 13.7)

13.6 (13.0 - 14.2)

15.5 (15.2 - 15.7)

Total PYLL‡

16.6 (16.3 - 16.9)

15.1 (14.8 - 15.4)

37.5 (36.9 - 38.0)

16.6 (16.1 - 17.1)

13.9 (13.2 - 14.6)

16.9 (16.6 - 17.1)

Men

Tobacco use

Overweight and Obesity

High Blood pressure

High cholesterol

High glycemia

Physical inactivity

Total AMI events (both fatal and non-fatal)

26.7 (26.2 - 27.1)

24.7 (24.1 - 25.2)

37.0 (36.4 - 37.6)

19.0 (18.3 - 19.6)

12.4 (11.8 - 13.0)

20.2 (19.8 - 20.6)

Total non-infarction events (both fatal and non-fatal)

23.1 (22.6 - 23.5)

22.3 (21.8 - 22.8)

40.1 (39.3 - 40.8)

19.3 (18.6 - 20.0)

13.5 (12.8 - 14.2)

20.6 (20.2 - 21.2)

Total stroke events (both fatal and non-fatal)

14.2 (13.7 - 14.7)

16.7 (16.0 - 17.3)

35.2 (34.3 - 36.0)

5.2 (4.9 - 5.5)

13.5 (12.6 - 14.4)

12.2 (11.7 - 12.6)

Total events (both fatal and non-fatal)

21.6 (21.1 - 22.0)

21.4 (20.9 - 21.9)

37.4 (36.7 - 38.1)

14.7 (14.1 - 15.2)

13.1 (12.4 - 13.8)

17.8 (17.4 - 18.2)

Total costs*

22.0 (21.6 - 22.5)

21.7 (21.2 - 22.2)

37.6 (36.8 - 38.2)

15.2 (14.7 - 15.8)

13.1 (12.4 - 13.8)

18.1 (17.7 - 18.6)

Total DALY†

22.1 (21.6 - 22.6)

20.5 (20.1 - 20.9)

38.7 (38.1 - 39.3)

12.1 (11.7 - 12.6)

13.0 (12.3 - 13.7)

15.6 (15.3 - 16.0)

Total PYLL‡

21.6 (21.1 - 22.1)

20.7 (20.2 - 21.1)

38.7 (38.1 - 39.3)

13.4 (12.9 - 13.8)

13.1 (12.4 - 13.8)

16.5 (16.2 - 16.9)

Women

Tobacco use

Overweight and Obesity

High Blood pressure

High cholesterol

High glycemia

Physical inactivity

Total AMI events (both fatal and non-fatal)

11.9 (11.5 - 12.3)

11.0 (10.5 - 11.6)

42.4 (41.1 - 43.5)

41.0 (39.2 - 42.7)

17.7 (16.2 - 19.1)

22.6 (22.2 - 23.1)

Total non-infarction events (both fatal and non-fatal)

8.5 (8.0 - 9.0)

10.5 (9.9 - 11.2)

42.5 (40.7 - 44.0)

41.1 (38.4 - 43.1)

17.7 (15.8 - 19.6)

23.7 (23.1 - 24.2)

Total stroke events (both fatal and non-fatal)

7.1 (6.8 - 7.6)

6.1 (5.8 - 6.5)

29.9 (28.9 - 30.8)

6.6 (6.1 - 7.1)

12.8 (11.5 - 14.2)

14.0 (13.6 - 14.3)

Total events (both fatal and non-fatal)

8.6 (8.3 - 9.1)

8.4 (8.0 - 8.9)

36.2 (34.9 - 37.3)

23.8 (22.4 - 24.9)

15.2 (13.8 - 16.8)

18.6 (18.1 - 19.0)

Total costs*

8.8 (8.4 - 9.3)

8.7 (8.2 - 9.7)

36.8 (35.5 - 37.9)

25.5 (24.1 - 26.7)

15.5 (14.0 - 17.0)

19.0 (18.6 - 19.5)

Total DALY†

10.5 (10.1 - 10.9)

7.6 (7.3 - 7.9)

34.5 (33.8 - 35.2)

14.5 (13.9 - 15.1)

14.1 (13.2 - 15.1)

15.3 (15.0 - 15.6)

Total PYLL‡

10.4 (10.0 - 10.8)

8.3 (7.9 - 8.7)

36.0 (35.0 - 36.9)

20.7 (19.7 - 21.6)

14.8 (13.6 - 16.0)

17.3 (16.9 - 17.6)

  1. Results of 1000 iterations, basal case, both sexes.
  2. 95%CI: 95% confidence interval, AMI: acute myocardial infarction, DALY: disability-adjusted life years, PYLL: Potential Years of Life Lost.
  3. * Only direct medical costs by hospitalization were considered.
  4. † With discounting (3% annual rate), without age weight.
  5. ‡ With discounting (3% annual rate).