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Table 1 Summary of statistical analysis plans

From: Impact of maternal metabolic abnormalities in pregnancy on human milk and subsequent infant metabolic development: methodology and design

Objective

Statistical technique

Outcome variable

Main exposures

Covariates

1

Linear regression

concentrations of metabolic hormones in colostrum (e.g. adiponectin)

maternal metabolic characteristics (e.g., glucose intolerance, insulin resistance, obesity)

maternal lifestyle, SES, medical history

2

Linear regression

concentrations of metabolic hormones in mature breast milk at 3 months postpartum

concentrations of metabolic hormones in colostrum

maternal lifestyle, SES, medical history, maternal metabolic characteristics

3

Linear regression

metabolic characteristics in offspring (e.g. infant growth, adiposity) during the first year of life

concentrations of metabolic hormones in colostrum

maternal lifestyle, SES, medical history, maternal metabolic characteristics, infant feeding/supplementation behaviors

4

Logistic regression

delayed onset of lactogenesis II

maternal metabolic characteristics (e.g., glucose intolerance, insulin resistance, obesity)

maternal lifestyle, SES, medical history

  1. Abbreviations: SES, socioeconomic status