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Table 3 Summary of the validation parameters for the LC-MS/MS methods for the determination of residual antibiotics in water samples from a hospital in Ujjain, India

From: Antibiotics and antibiotic-resistant bacteria in waters associated with a hospital in Ujjain, India

Antibiotics

Correlation coefficient r2

Coefficient of Variation (%RSD)

LOD ÎŒg/l

LOQ ÎŒg/l

% Recovery n = 5

  

Interday n = 6

Intraday n = 6

   

Amoxicillin

0.994

5.2

5.6

0.5

1.0

85 (%RSD 5.6)

Ceftrixone

0.997

2.1

1.8

2.5

5.0

84 (%RSD 4.1)

Amikacin

0.990

4.8

4.3

0.25

0.5

92 (%RSD 3.8)

Ofloxacin

0.999

3.1

2.57

0.01

0.025

95 (%RSD 3.7)

Ciprofloxacin

0.999

3.2

3.03

0.01

0.025

98 (%RSD 4.5)

Norfloxacin

0.999

3.4

3.02

0.01

0.025

90 (%RSD 3.2)

Levofloxacin

0.999

3.12

2.96

0.01

0.025

93 (%RSD 2.8)

  1. LOD: Limit of detection; LOQ: Limit of quantification