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Table 7 Multivariate analysis of 231 cases treated at least 24 hours, odds ratio for death or other unfavourable (transfer out, default, physician's decision to stop early) outcomes.

From: Treatment outcome of extra-pulmonary tuberculosis in Finland: a cohort study

Variable

Death

Other unfavourable

All unfavourable (death and other) together

  

N

OR (95% CI)

p

N

OR (95% CI)

p

N

OR (95% CI)

p

Sex

female

15

1

 

26

1

 

41

1

 
 

male

17

8.53 (3.23-22.50)

<0.001

16

1.24 (0.55-2.84)

0.61

33

2.04 (0.98-4.24)

0.06

Age at diagnosis

risk per five years

 

1.10 (1.06-1.14)

<0.001

 

1.01 (0.98-1.04)

0.30

 

1.16 (1.03-1.31)

0.02

Immunosuppression

no

22

1

 

38

1

 

60

1

 
 

yes

10

5.58 (1.92-16.21)

0.002

4

1.22 (0.38-3.90)

0.74

14

2.07 (1.33-3.22)

0.001

TB history

no

30

1

 

35

1

 

75

1

 
 

yes

2

0.27 (0.05-1.59)

0.15

7

1.04 (0.44-2.43)

0.93

9

0.74 (0.32-1.70)

0.48

Site of tuberculosis

superficial

13

1

 

26

1

 

39

1

 
 

deep

19

1.48 (0.68-3.20)

0.32

16

0.46 (0.24-0.86)

0.02

35

0.62 (0.38-1.03)

0.07

Specialty responsible for ending treatment

pulmonary

8

1

 

34

1

 

42

1

 
 

internal medicine

7

6.85 (2.24-20.97)

0.001

5

1.09 (0.32-3.72)

0.90

12

1.89 (0.86-4.14)

0.11

 

general medicine

16

28.91 (5.95-140.51)

<0.001

2

0.33 (0.08-1.38)

0.13

18

2.59 (0.97-6.91)

0.06

 

other

1

173.65 (12.97-2325.22)

<0.001

1

1.99 (0.79-5.01)

0.14

2

5.27 (1.48-18.73)

0.01

Pause of treatment

no

25

1

 

22

1

 

47

1

 
 

yes

7

0.25 (0.58-1.07)

0.06

20

2.48 (0.92-6.69)

0.07

27

1.28 (0.54-3.07)

0.58

Treatment group

standard treatment A

18

1

 

17

1

 

35

1

 
 

standard treatment B

5

3.88 (0.89-16.87)

0.07

9

3.67 (1.52-8.85)

0.004

14

4.32 (2.00-9.31)

<0.001

 

standard treatment C

1

1.49 (0.27-8.12)

0.65

2

0.75 (0.14-4.00)

0.73

3

0.98 (0.22-4.27)

0.98

 

standard treatment D

1

1.26 (0.10-16.51)

0.86

5

2.52 (0.50-12.80)

0.27

6

2.46 (0.76-8.00)

0.13

 

other combination

6

5.06 (1.13-22.57)

0.03

9

1.47 (0.35-6.24)

0.60

15

2.02 (0.56-7.31)

0.28

 

ineffective

1

3.44 (0.54-22.00)

0.19

0

0

<0.001

1

0.59 (0.11-3.20)

0.54

  1. Significant p-values are darkened.
  2. Reference category is favourable treatment outcome.