From: Treatment outcome of extra-pulmonary tuberculosis in Finland: a cohort study
Variable | Death | Other unfavourable | All unfavourable (death and other) together | |||||||
---|---|---|---|---|---|---|---|---|---|---|
N | OR (95% CI) | p | N | OR (95% CI) | p | N | OR (95% CI) | p | ||
Sex | female | 15 | 1 | 26 | 1 | 41 | 1 | |||
male | 17 | 8.53 (3.23-22.50) | <0.001 | 16 | 1.24 (0.55-2.84) | 0.61 | 33 | 2.04 (0.98-4.24) | 0.06 | |
Age at diagnosis | risk per five years | 1.10 (1.06-1.14) | <0.001 | 1.01 (0.98-1.04) | 0.30 | 1.16 (1.03-1.31) | 0.02 | |||
Immunosuppression | no | 22 | 1 | 38 | 1 | 60 | 1 | |||
yes | 10 | 5.58 (1.92-16.21) | 0.002 | 4 | 1.22 (0.38-3.90) | 0.74 | 14 | 2.07 (1.33-3.22) | 0.001 | |
TB history | no | 30 | 1 | 35 | 1 | 75 | 1 | |||
yes | 2 | 0.27 (0.05-1.59) | 0.15 | 7 | 1.04 (0.44-2.43) | 0.93 | 9 | 0.74 (0.32-1.70) | 0.48 | |
Site of tuberculosis | superficial | 13 | 1 | 26 | 1 | 39 | 1 | |||
deep | 19 | 1.48 (0.68-3.20) | 0.32 | 16 | 0.46 (0.24-0.86) | 0.02 | 35 | 0.62 (0.38-1.03) | 0.07 | |
Specialty responsible for ending treatment | pulmonary | 8 | 1 | 34 | 1 | 42 | 1 | |||
internal medicine | 7 | 6.85 (2.24-20.97) | 0.001 | 5 | 1.09 (0.32-3.72) | 0.90 | 12 | 1.89 (0.86-4.14) | 0.11 | |
general medicine | 16 | 28.91 (5.95-140.51) | <0.001 | 2 | 0.33 (0.08-1.38) | 0.13 | 18 | 2.59 (0.97-6.91) | 0.06 | |
other | 1 | 173.65 (12.97-2325.22) | <0.001 | 1 | 1.99 (0.79-5.01) | 0.14 | 2 | 5.27 (1.48-18.73) | 0.01 | |
Pause of treatment | no | 25 | 1 | 22 | 1 | 47 | 1 | |||
yes | 7 | 0.25 (0.58-1.07) | 0.06 | 20 | 2.48 (0.92-6.69) | 0.07 | 27 | 1.28 (0.54-3.07) | 0.58 | |
Treatment group | standard treatment A | 18 | 1 | 17 | 1 | 35 | 1 | |||
standard treatment B | 5 | 3.88 (0.89-16.87) | 0.07 | 9 | 3.67 (1.52-8.85) | 0.004 | 14 | 4.32 (2.00-9.31) | <0.001 | |
standard treatment C | 1 | 1.49 (0.27-8.12) | 0.65 | 2 | 0.75 (0.14-4.00) | 0.73 | 3 | 0.98 (0.22-4.27) | 0.98 | |
standard treatment D | 1 | 1.26 (0.10-16.51) | 0.86 | 5 | 2.52 (0.50-12.80) | 0.27 | 6 | 2.46 (0.76-8.00) | 0.13 | |
other combination | 6 | 5.06 (1.13-22.57) | 0.03 | 9 | 1.47 (0.35-6.24) | 0.60 | 15 | 2.02 (0.56-7.31) | 0.28 | |
ineffective | 1 | 3.44 (0.54-22.00) | 0.19 | 0 | 0 | <0.001 | 1 | 0.59 (0.11-3.20) | 0.54 |