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Table 2 Distribution of the Val66Met (G196A) genotypes according to the longitudinal evolution of the risk and diagnosis of ED

From: BDNF Val66Met polymorphism, energy intake and BMI: a follow-up study in schoolchildren at risk of eating disorders

Evolution of risk Evolution of diagnosis
  Val/Vala Val/Metb Met/Metc    Val/Vala Val/Metb Met/Metc   
  n
% (95% CI)
n
% (95% CI)
n
% (95% CI)
p-value p-value a vs b+c n
% (95% CI)
n
% (95% CI)
n
% (95% CI)
p-value p-value a vs b+c
No→No 42
66.7 (53.7-78.0)
16
25.4 (15.3-37.9)
5
7.9 (2.6-17.6)
   89
68.5 (60.5-76.4)
35
26.9 (19.3-34.5)
6
4.6 (1.7-9.8)
  
Yes→No 49
66.2 (54.3-76.8)
23
31.1 (20.8-42.9)
2
2.7 (0.3-9.4)
0.381 0.343 9
50.0 (26.0-74.0)
8
44.4 (21.5-69.2)
1
5.6 (0.1-27.3)
0.797 0.298
No→Yes 5
41.7 (15.2-72.3)
6
50.0 (21.1-78.9)
1
8.3 (0.2-38.5)
   18
64.3 (44.1-81.4)
8
28.6 (13.2-48.7)
2
7.1 (0.9-23.5)
  
Yes→Yes 35
72.9 (58.2-84.7)
11
22.9 (12.0-37.3)
2
4.2 (0.5-14.3)
   15
71.4 (47.8-88.7)
5
23.8 (8.2-47.2)
1
4.8 (0.1-23.8)
  
  1. CI: confidence interval; No→No: no risk/diagnosis in either preadolescence or adolescence; Yes→No: risk/diagnosis in preadolescence but no risk/diagnosis in adolescence; No→Yes: no risk/diagnosis in preadolescence but risk/diagnosis in adolescence; Yes→Yes: risk/diagnosis in both preadolescence and adolescence.
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