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Table 2 Distribution of the Val66Met (G196A) genotypes according to the longitudinal evolution of the risk and diagnosis of ED

From: BDNF Val66Met polymorphism, energy intake and BMI: a follow-up study in schoolchildren at risk of eating disorders

Evolution of risk

Evolution of diagnosis

 

Val/Vala

Val/Metb

Met/Metc

  

Val/Vala

Val/Metb

Met/Metc

  
 

n

% (95% CI)

n

% (95% CI)

n

% (95% CI)

p-value

p-value a vs b+c

n

% (95% CI)

n

% (95% CI)

n

% (95% CI)

p-value

p-value a vs b+c

No→No

42

66.7 (53.7-78.0)

16

25.4 (15.3-37.9)

5

7.9 (2.6-17.6)

  

89

68.5 (60.5-76.4)

35

26.9 (19.3-34.5)

6

4.6 (1.7-9.8)

  

Yes→No

49

66.2 (54.3-76.8)

23

31.1 (20.8-42.9)

2

2.7 (0.3-9.4)

0.381

0.343

9

50.0 (26.0-74.0)

8

44.4 (21.5-69.2)

1

5.6 (0.1-27.3)

0.797

0.298

No→Yes

5

41.7 (15.2-72.3)

6

50.0 (21.1-78.9)

1

8.3 (0.2-38.5)

  

18

64.3 (44.1-81.4)

8

28.6 (13.2-48.7)

2

7.1 (0.9-23.5)

  

Yes→Yes

35

72.9 (58.2-84.7)

11

22.9 (12.0-37.3)

2

4.2 (0.5-14.3)

  

15

71.4 (47.8-88.7)

5

23.8 (8.2-47.2)

1

4.8 (0.1-23.8)

  
  1. CI: confidence interval; No→No: no risk/diagnosis in either preadolescence or adolescence; Yes→No: risk/diagnosis in preadolescence but no risk/diagnosis in adolescence; No→Yes: no risk/diagnosis in preadolescence but risk/diagnosis in adolescence; Yes→Yes: risk/diagnosis in both preadolescence and adolescence.