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Table 1 Model input parameters and outputs

From: Estimating the magnitude and direction of bias in tuberculosis drug resistance surveys conducted only in the public sector: a simulation study

Parameter Meaning Notes on values; (allowable ranges)
Inputs
Λ TB incidence rate (new cases) Fixed incidence (value irrelevant)
k FN Fraction of new cases that go to the public sector (0-1)
k RN Fraction of retreatment cases that go to the public sector (0-1)
y t Fraction of new cases that are sensitive 1-qC Where q is the relative transmissibility of resistant compared with sensitive strains (range of q from 0-1; assumes no resistant "superbugs") and C (range of C from 0-1) is the proportion of all incident cases with MDR
x S Fraction of new sensitive cases that go to the public sector (0-1)
x R Fraction of new resistant cases that go to the public sector (0-1)
f R , f S
f •N , f •P
Fraction failing treatment among drug resistant and sensitive
Fraction failing treatment in public and private sectors
f S f R Failure more likely for resistant
and
f •N f •P Failure as or more likely in private sector
a N ,a P Fraction of TB cases in the public and private sectors who acquire resistance (0-1) a N a P Acquired resistance as or more likely in private sector
l Fraction that are lost to follow-up or die (0-1)
r N Fraction in the public sector that return to the public sector for next treatment episode Retreatment cases more likely to present in public sector
r P Fraction in the private sector that return to the private sector for next treatment episode Retreatment cases more likely to present in public sector
Outputs
A Proportion of new cases with resistant TB
A N Proportion of new cases in public sector with resistant TB
A P Proportion of new cases in private sector with resistant TB
B Proportion of retreatment cases with resistant TB
B N Proportion of retreatment cases in public sector with resistant TB
B P Proportion of retreatment cases in private sector with resistant TB
C Proportion of all cases with resistant TB
C N Proportion of all cases in public sector with resistant TB
C P Proportion of all cases in private sector with resistant TB