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Table 2 Age-adjusted OR(95%CI) of dementia and its subtypes in people with subclinical hyperthyroidism compared to normal thyroid function.

From: Subclinical hyperthyroidism and dementia: the Sao Paulo Ageing & Health Study (SPAH)

  Model Odds ratio
(95% CI)
All (n = 33) subclinical hyperthyroidism   
Any type of dementia
(n = 49)
Crude 3.2 (1.1-9.5)
  Age-adjusted 4.1 (1.3-13.1)
  Multivariate adjusted* 4.9 (1.5-15.7)
Alzheimer Disease
(n = 19)
Crude 1.9 (0.2-14.3)
  Age-adjusted 2.1 (0.3-17.3)
  Multivariate adjusted* 2.5 (0.3-20.8)
Vascular dementia
(n = 18)
Crude 4.3 (1.0-19.6)
  Age-adjusted 5.3 (1.1-26.4)
  Multivariate adjusted* 6.7 (1.4-33.1)
Men (n = 10) subclinical hyperthyroidism   
Any type of dementia
(n = 16)
Crude 7.5 (1.5-38.4)
  Age-adjusted 8.0 (1.5-43.4)
  Multivariate adjusted* 8.1 (1.5-44.6)
Alzheimer Disease
(n = 5)
Crude 11.9 (1.2-117.0)
  Age-adjusted 12.4 (1.2-128.4)
  Multivariate adjusted* 11.6 (1.1-120.7)
Vascular dementia
(n = 9)
Crude 5.9 (0.7-52.0)
  Age-adjusted 6.1 (0.7-56.3)
  Multivariate adjusted* 5.8 (0.6-54.4)
Women (n = 23) subclinical hyperthyroidism)   
Any type of dementia
(n = 33)
Crude 1.9 (0.4-8.5)
  Age-adjusted 2.6 (0.5-13.6)
  Multivariate adjusted* 3.4 (0.7-17.3)
Vascular dementia
(n = 9)
Crude 3.7 (0.4-30.6)
  Age-adjusted 5.0 (0.5-55.0)
  Multivariate adjusted* 9.2 (0.9-96.4)
  1. *Multivariate adjusted include adjustment for age and body-mass index.