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Table 4 Cost-effectiveness of rotavirus vaccination in the GAVI-eligible countries

From: Health and economic impact of rotavirus vaccination in GAVI-eligible countries

Country Base-case vaccine efficacy (adjusted for serotype distribution) Vaccine efficacy based on SAGE recommendation
  ICERa(I$/DALY averted) I$10 per vaccinated child ICERa(I$/DALY averted) I$25 per vaccinated child ICERb(I$/DALY averted) based on GAVI's co-financing scheme ICERa(I$/DALY averted) I$10 per vaccinated child ICERa(I$/DALY averted) I$25 per vaccinated child ICERb(I$/DALY averted) based on GAVI's co-financing scheme
AFR D       
   Angola saving 26 4 0.2 68 22
   Benin 25 108 52 57 190 87
   Burkina Faso 22 90 37 42 141 59
   Cameroon 22 108 57 54 190 93
   Chad saving 54 33 17 113 59
   Comoros 119 341 150 122 348 153
   Ghana 71 221 100 142 398 176
   Guinea 18 99 54 49 178 88
   Guinea-Bissau 7 68 37 26 113 57
   Liberia 17 67 32 37 114 53
   Madagascar 20 124 65 60 225 108
   Mali 5 58 29 26 109 51
   Mauritania 21 116 52 58 209 92
   Niger saving 36 23 10 78 42
   Nigeria 27 102 48 51 162 74
   Sao Thome 40 152 65 83 262 112
   Senegal 32 125 56 68 215 95
   Sierra Leone 2 41 21 17 79 37
   The Gambia 59 196 87 112 328 145
   Togo 46 155 75 88 262 121
AFR E       
   Burundi 22 84 44 46 145 70
   Central African Republic 20 96 46 50 171 78
   Congo 74 250 111 143 422 185
   Cote d'Ivoire 21 95 47 44 153 72
   Democratic Republic of the Congo 19 76 39 41 131 62
   Eritrea 95 266 117 97 272 120
   Ethiopia 28 98 45 55 166 74
   Kenya 37 150 68 81 260 115
   Lesotho 397 1,061 459 655 1,707 737
   Malawi 26 93 40 55 165 71
   Mozambique 31 115 48 64 198 83
   Rwanda 1 58 30 23 114 54
   Tanzania 42 147 66 87 258 114
   Uganda 31 127 62 68 220 102
   Zambia 23 103 45 49 166 72
   Zimbabwe 78 251 110 134 391 170
AMR A, B & D       
   Cuba 11,332 28,443 12,240 11,909 29,888 12,862
   Guyana 4 113 40 7 122 44
   Honduras 85 386 190 95 411 201
   Bolivia 47 246 120 53 262 128
   Haiti 4 105 56 46 212 102
   Nicaragua 217 646 289 234 688 307
EMR D       
   Afghanistan saving 47 29 15 90 48
   Djibouti saving 90 54 25 179 92
   Pakistan 42 192 102 95 325 159
   Somalia saving 39 32 11 83 51
   Sudan 84 266 121 148 426 190
   Yemen 26 160 82 73 276 132
EUR B & C       
   Armenia 227 685 312 254 753 341
   Azerbaijan saving 95 68 35 223 123
   Georgia 131 429 206 148 473 225
   Kyrgyzstan 59 215 99 68 239 109
   Tajikistan 6 80 48 10 91 53
   Uzbekistan saving 122 58 saving 144 67
   Moldova 1,763 4,497 1,949 1,925 4,900 2,122
   Ukraine 4,816 12,161 5,243 5,249 13,245 5,710
SEAR B & D       
   Indonesia 80 302 136 90 326 146
   Korea, Democratic Republic 118 363 154 129 390 165
   Sri Lanka 487 1,303 565 522 1,391 603
   Timor Leste 41 161 67 46 174 73
   Bangladesh 50 209 104 52 216 106
   Bhutan 38 175 75 44 190 81
   India 54 201 97 53 198 96
   Myanmar 28 137 74 75 256 126
   Nepal 62 215 102 70 235 110
WPR B       
   Cambodia saving 44 34 10 111 63
   Kiribati 4 111 50 9 122 54
   Lao People Democratic Republic 15 132 77 20 144 83
   Mongolia 77 274 114 85 296 123
   Papua New Guinea saving 84 36 saving 95 41
   Solomon Islands 143 444 186 156 476 200
   Viet Nam 193 799 390 228 885 427
  1. I$ = International dollars; DALY = Disability-adjusted life year; ICER = Incremental cost-effectiveness ratio.
  2. AFR = African Region; EMR = Eastern Mediterranean Region; EUR = European Region; AMR = Region of the Americas; WPR = Western Pacific Region; SEAR = South-East Asian Region.
  3. a ICERs are for a strategy of vaccinating 70% of a single birth cohort born in 2010 assuming a vaccination program cost of I$10 and I$25 per vaccinated child compared to no vaccination.
  4. b ICERs are for a strategy of vaccinating 70% of a single birth cohort born in 2010, but vaccination program costs vary across countries according to the GAVI's co-financing scheme [32].