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Table 2 Definitions and criteria used to collect respiratory and cardiovascular risk factors and main comorbidities among cohort members in the CAPAMIS Study.*

From: Rationale and design of the CAPAMIS study: Effectiveness of pneumococcal vaccination against community-acquired pneumonia, acute myocardial infarction and stroke

History of prior pneumonia Includes influenza-related pneumonia (J10.0 and J11.0), viral pneumonia (J12), pneumococcal pneumonia (J13), pneumonia due to Haemophillus influenzae (J14), bacterial pneumonia (J15), pneumonia due to other infectious organisms (J16), pneumonia in diseases classified elsewhere (J17) and pneumonia due to unspecified microorganisms (J18).
History of coronary artery disease Includes angina (I20), acute myocardial infarction (I21), subsequent or recurrent myocardial infarction (I22) and chronic ischaemic heart disease (I25).
History of stroke Includes haemorrhagic stroke (I60 to I62), cerebral infarction (I63) and stroke not specified as haemorrhage or infarction (I64); it does not include transient ischaemic attacks (code G45).
Hypertension Defined as the presence of any code I10, I11, I12, I13 or I15.
Hypercholesterolemia Defined as the presence of code E78.
Diabetes mellitus Codes E10 to E14.
Obesity Patients with registered code E66 (BMI>30%).
Smoking Includes patients with current smoking (code F17 active at study start).
Alcoholism Includes patients with code F10 active at study start.
History of heart disease Includes congestive heart failure (I50), hypertensive heart disease (I11), cardiomyopathy (I42), cardiac dilatation or ventricular hypertrophy (I11.9 or I51.7) and coronary artery disease (I20, I21, I22 and I25).
History of vascular ischaemia Besides coronary artery disease and stroke, it Includes atheroesclerosis (I70), acute arterial embolism or thrombosis (I74) and peripheric arterial disease or intermittent claudication (I73.9).
Chronic pulmonary disease Includes chronic bronchitis or emphysema (J42 to J44) and asthma: (J45).
Severe liver disease Includes chronic viral hepatitis (B18), alcoholic hepatitis (K70) and cirrhosis (K74).
Severe nephropathy Includes nephrotic syndrome (N04 or N39.1), renal failure (N18, N19) and kidney dialysis (Y84.1) or transplantation.
Immunocompromise Defined as the presence of any immunodeficiency (D80 to D84), AIDS (B20 to B24), anatomic or functional asplenia (D73.0 and Q89.0), cancer, severe nephropaty, or long-term corticosteroid therapy (20 mg/day of prednisone or equivalent).
  1. * Data will be considered at the beginning of the study, and it will be defined according to the International Classification of Diseases 10th Revision (ICD-10) codes registered in the primary care clinical record of each cohort member at the start of the study.