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Table 1 Detailed description of each component of the transmission function

From: Analysis of the effectiveness of interventions used during the 2009 A/H1N1 influenza pandemic

Component of transmission function Description
P trans ( I i , I s ) Probability of disease transmission from infected to susceptible individual.
β Disease transmission coefficient, chosen to achieve baseline epidemics with specific R0 values.
Susc( I s ) Age specific susceptibility of infectee or susceptible individual.
Inf t ( I i ) Infectiousness of infector as a function of time since infection and symptomatic status.
AVF( I i , I s ) Antiviral factor which reduces transmission probability when antiviral based interventions are applied to individuals I i , I s or both.
The following different situations may arise when we model antiviral effectiveness.
AVF( I i , I s ) = 1 - AVE i if the infected individual is treated with antiviral drugs and no antiviral prophylaxis is applied to the susceptible individual
AVF( I i , I s ) = 1 - AVE s if antiviral prophylaxis are applied to the susceptible individual and no antiviral treatment is used with the infected individual
AVF( I i , I s ) = (1-AVE i )*(1-AVE s ) if both infected and susceptible individuals are receiving antiviral drugs for treatment and prophylaxis respectively
AVF( I i , I s ) = 1 if neither infector nor susceptible individuals are receiving antiviral drugs