Table 2 Treatment related characteristics associated with non-cure after anti-tuberculosis treatment in patients diagnosed in 30 remote and poor counties in Shaanxi province, China
Treatment characteristic | n(%) | Treatment result | OR | 95% CI | p-value | |
|---|---|---|---|---|---|---|
| Â | Â | Uncured (%) | Cured (%) | Â | Â | Â |
Co-morbidity | Â | Â | Â | Â | Â | < 0.01 |
No | 562 (93.0) | 95 (16.9) | 467 (83.1) | 1 | Â | Â |
Yes | 42 (7.0) | 22 (52.4) | 20 (47.6) | 5.41 | 2.84-10.30 | Â |
Fever | Â | Â | Â | Â | Â | 0.04 |
No | 426 (66.7) | 99(23.9) | 327 (76.1) | 1 | Â | Â |
Yes | 213 (33.3) | 34 (16.0) | 179 (84.0) | 1.59 | 1.04-2.45 | Â |
Loss of appetite | Â | Â | Â | Â | Â | < 0.01 |
No | 497 (77.8) | 92 (18.5) | 405 (81.5) | Â | Â | Â |
Yes | 142 (22.2) | 41 (28.9) | 101 (71.1) | 1.79 | 1.17-2.74 | Â |
Institute where TB was diagnosed | Â | Â | Â | Â | Â | 0.01 |
CDC | 142 (22.2) | 60 (17.1) | 290 (82.9) | 1 | Â | Â |
Other | 497 (77.8) | 73 (25.3) | 216 (74.7) | 1.63 | 1.11-2.40 | Â |
DOT supervisor | Â | Â | Â | Â | Â | < 0.01 |
No supervisor | 169 (26.4) | 48 (28.4) | 121 (71.6) | 1 | Â | Â |
Family | 367 (57.4) | 73 (19.9) | 294 (80.1) | 0.63 | 0.41-0.95 | Â |
Doctor | 103 (16.1) | 12 (11.7) | 91 (88.3) | 0.33 | 0.17-0.66 | Â |
Number of times forgotten to take drugs | Â | Â | Â | Â | Â | < 0.01 |
none | 541 (84.7) | 104 (19.2) | 437 (80.8) | 1 | Â | Â |
≤9 times | 76 (11.9) | 18 (23.7) | 58 (76.3) | 1.30 | 0.74-2.31 |  |
>9 times | 22 (3.4) | 11 (50.0) | 11 (50.0) | 4.20 | 1.77-9.96 | Â |
Maximum number of subsequently missed doses | Â | Â | Â | Â | Â | 0.01 |
None | 542 (84.8) | 105 (19.4) | 437 (80.6) | 1 | Â | Â |
≤ 3 times | 64 (10.0) | 14 (21.9) | 50 (78.1) | 1.17 | 0.62-2.19 |  |
>3 times | 33 (5.2) | 14 (42.4) | 19 (57.6) | 3.07 | 1.49-6.32 | Â |
Interruption of treament | Â | Â | Â | Â | Â | < 0.01 |
No | 591 (92.5) | 102 (17.3) | 489 (82.7) | 1 | Â | Â |
Yes | 48 (7.5) | 31 (64.6) | 17 (35.4) | 8.74 | 4.66-16.40 | Â |
Severity of side effects* | Â | Â | Â | Â | Â | < 0.01 |
None | 361 (56.5) | 66 (18.3) | 295 (81.7) | 1 | Â | Â |
Severe | 54 (8.5) | 27 (50.0) | 27 (50.0) | 4.47 | 2.46-8.12 | Â |
Medium | 41 (6.4) | 14 (34.1) | 27 (65.9) | 2.32 | 1.15-4.66 | Â |
Light | 183 (28.6) | 26 (14.2) | 157 (85.8) | 0.74 | 0.45-1.21 | Â |
Sputum re-examination** | Â | Â | Â | Â | Â | < 0.01 |
Regular | 442 (69.2) | 57 (12.9) | 385 (87.1) | 1 | Â | Â |
Irregular | 155 (24.3) | 59 (38.1) | 96 (61.9) | 4.15 | 2.71-6.36 | Â |
None | 42 (6.6) | 17 (40.5) | 25 (59.5) | 4.59 | 2.34-9.03 | Â |