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Table 5 Association between health-related variables and ART adherence

From: Antiretroviral treatment adherence among HIV patients in KwaZulu-Natal, South Africa

  

VAS adherence (≥ 95%)

Dose, schedule and food adherence

 

N (%)

519

Crude OR

(95% CI)

P

Adjusted ORa, b

(95% CI)

P

Crude OR

(95% CI)

P

Adjusted ORa, c

(95% CI)

P

Time since diagnosis

         

2006-1995

125 (24.8)

1.00

   

1.00

   

2007/8

379 (75.2)

0.49 (0.26-0.92)

.026

...

 

0.80 (0.50-1.26)

.330

---

 

Hospital admission in the past 6 months

         

No

463 (89.7)

1.00

   

1.00

   

Yes

53 (10.3)

1.51 (0.62-3.69)

.326

...

 

0.98 (0.51-1.85)

.937

---

 

CD4 count

         

≤ 200

420 (83.2)

1.00

 

...

 

1.00

 

1.00

 

>200

85 (16.8)

1.19 (0.63-2.26)

.599

  

2.90 (1.52-5.53)

.001

3.32 (1.18-9.38)

.023

HIV symptoms (range 0-20)

         

M (SD)

1.2 (2.6)

1.08 (0.96-1.21)

.213

...

 

1.06 (0.97-1.15)

.199

---

 

Overall Quality of Life d

         

M (SD)

4.3 (0.7)

2.87 (2.00-4.10)

.000

0.94 (0.52-1.68)

.830

3.91 (2.71-5.65)

.000

2.06 (1.07-3.98)

.031

General health perceptionsd

         

M (SD)

4.4 (0.7)

2.69 (1.95-3.73)

.000

1.72 (1.01-2.95)

.047

3.72 (2.62-5.28)

.000

1.57 (0.89-2.79)

.121

WHOQOL-HIV BREFscores

         

Physical domaine

15.6 (2.7)

1.35 (1.22-1.49)

.000

0.94 (0.78-1.13)

.512

1.54 (1.40-1.69)

.000

0.87 (0.70-1.08)

.201

Psychological domaine

14.6 (3.2)

1.40 (1.28-1.53)

.000

1.17 (0.97-1.41)

.099

1.65 (1.50-1.81)

.000

1.00 (0.81-1.23)

.970

Level of independence domaine

14.5 (1.9)

1.42 (1.29-1.56)

.080

...

 

1.10 (0.98-1.24)

.103

...

 

Social relationships domaine

13.4 (2.6)

1.52 (1.37-1.69)

.000

1.14 (1.00-1.30)

.048

1.65 (1.49-1.83)

.000

1.05 (0.89-1.24)

.549

Environment domaine

13.9 (2.6)

1.76 (1.56-2.00)

.000

1.56 (1.28-1.89)

.000

2.46 (2.11-2.87)

.000

2.21 (1.71-2.86)

.000

Spirituality/religion/personal beliefs domaine

15.3 (2.9)

1.17 (1.08-1.27)

.000

0.76 (0.63-0.91)

.003

1.40 (1.29-1.51)

.000

1.06 (0.89-1.28)

.507

Depression score (higher score = more depressed)

17.3 (3.3)

0.78 (0.72-0.84)

.000

0.88 (0.80-0.96)

.006

0.63 (0.58-0.69)

.000

0.71 (0.62-0.80)

.000

ART regimen

         

3TC, d4T + Efavirenz

411 (79.2)

1.00

 

1.00

 

1.00

 

1.00

 

3TC, d4T + Nevirapine

108 (20.8)

4.08 (1.73-9.63)

.001

2.16 (0.80-5.87)

.130

5.25 (2.57-10.72)

.000

4.61 (1.48-14.34)

.008

  1. aUsing block entry;bHosmer and Lemeshow Chi-square = 11.67, df = 8, p = .166; bCox & Snell R2 .26; b Nagelkerke R2 .42;
  2. cHosmer and Lemeshow Chisquare = 25.05, df = 8, p.002; cCox & Snell R2 .54; c Nagelkerke R2 .76
  3. d Mean scores range from 1 to 5, with 5 indicating the highest, most positive perceptions of quality of life or general health perceptions.
  4. e Overall domain scores range from 4 to 20, with 20 indicating the highest, most positive perceptions.
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BMC Public Health

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