Skip to main content

Table 5 Association between health-related variables and ART adherence

From: Antiretroviral treatment adherence among HIV patients in KwaZulu-Natal, South Africa

   VAS adherence (≥ 95%) Dose, schedule and food adherence
  N (%)
519
Crude OR
(95% CI)
P Adjusted ORa, b
(95% CI)
P Crude OR
(95% CI)
P Adjusted ORa, c
(95% CI)
P
Time since diagnosis          
2006-1995 125 (24.8) 1.00     1.00    
2007/8 379 (75.2) 0.49 (0.26-0.92) .026 ...   0.80 (0.50-1.26) .330 ---  
Hospital admission in the past 6 months          
No 463 (89.7) 1.00     1.00    
Yes 53 (10.3) 1.51 (0.62-3.69) .326 ...   0.98 (0.51-1.85) .937 ---  
CD4 count          
≤ 200 420 (83.2) 1.00   ...   1.00   1.00  
>200 85 (16.8) 1.19 (0.63-2.26) .599    2.90 (1.52-5.53) .001 3.32 (1.18-9.38) .023
HIV symptoms (range 0-20)          
M (SD) 1.2 (2.6) 1.08 (0.96-1.21) .213 ...   1.06 (0.97-1.15) .199 ---  
Overall Quality of Life d          
M (SD) 4.3 (0.7) 2.87 (2.00-4.10) .000 0.94 (0.52-1.68) .830 3.91 (2.71-5.65) .000 2.06 (1.07-3.98) .031
General health perceptionsd          
M (SD) 4.4 (0.7) 2.69 (1.95-3.73) .000 1.72 (1.01-2.95) .047 3.72 (2.62-5.28) .000 1.57 (0.89-2.79) .121
WHOQOL-HIV BREFscores          
Physical domaine 15.6 (2.7) 1.35 (1.22-1.49) .000 0.94 (0.78-1.13) .512 1.54 (1.40-1.69) .000 0.87 (0.70-1.08) .201
Psychological domaine 14.6 (3.2) 1.40 (1.28-1.53) .000 1.17 (0.97-1.41) .099 1.65 (1.50-1.81) .000 1.00 (0.81-1.23) .970
Level of independence domaine 14.5 (1.9) 1.42 (1.29-1.56) .080 ...   1.10 (0.98-1.24) .103 ...  
Social relationships domaine 13.4 (2.6) 1.52 (1.37-1.69) .000 1.14 (1.00-1.30) .048 1.65 (1.49-1.83) .000 1.05 (0.89-1.24) .549
Environment domaine 13.9 (2.6) 1.76 (1.56-2.00) .000 1.56 (1.28-1.89) .000 2.46 (2.11-2.87) .000 2.21 (1.71-2.86) .000
Spirituality/religion/personal beliefs domaine 15.3 (2.9) 1.17 (1.08-1.27) .000 0.76 (0.63-0.91) .003 1.40 (1.29-1.51) .000 1.06 (0.89-1.28) .507
Depression score (higher score = more depressed) 17.3 (3.3) 0.78 (0.72-0.84) .000 0.88 (0.80-0.96) .006 0.63 (0.58-0.69) .000 0.71 (0.62-0.80) .000
ART regimen          
3TC, d4T + Efavirenz 411 (79.2) 1.00   1.00   1.00   1.00  
3TC, d4T + Nevirapine 108 (20.8) 4.08 (1.73-9.63) .001 2.16 (0.80-5.87) .130 5.25 (2.57-10.72) .000 4.61 (1.48-14.34) .008
  1. aUsing block entry;bHosmer and Lemeshow Chi-square = 11.67, df = 8, p = .166; bCox & Snell R2 .26; b Nagelkerke R2 .42;
  2. cHosmer and Lemeshow Chisquare = 25.05, df = 8, p.002; cCox & Snell R2 .54; c Nagelkerke R2 .76
  3. d Mean scores range from 1 to 5, with 5 indicating the highest, most positive perceptions of quality of life or general health perceptions.
  4. e Overall domain scores range from 4 to 20, with 20 indicating the highest, most positive perceptions.