TY - JOUR AU - Marks, Peter J. AU - Neal, Keith R. PY - 2001 DA - 2001/12/11 TI - Variations in chemoprophylaxis for meningococcal disease: a retrospective case note review, analysis of routine prescribing data and questionnaire of general practitioners JO - BMC Public Health SP - 16 VL - 1 IS - 1 AB - Invasive meningococcal disease is a significant cause of mortality and morbidity in the UK. Administration of chemoprophylaxis to close contacts reduces the risk of a secondary case. However, unnecessary chemoprophylaxis may be associated with adverse reactions, increased antibiotic resistance and removal of organisms, such as Neisseria lactamica, which help to protect against meningococcal disease. Limited evidence exists to suggest that overuse of chemoprophylaxis may occur. This study aimed to evaluate prescribing of chemoprophylaxis for contacts of meningococcal disease by general practitioners and hospital staff. SN - 1471-2458 UR - https://doi.org/10.1186/1471-2458-1-16 DO - 10.1186/1471-2458-1-16 ID - Marks2001 ER -