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Table 2 Categorical or continuous WHtR and mortality by Cox proportional hazards model

From: Association of anthropometric measures with all-cause and cause-specific mortality in US adults: revisiting the obesity paradox

WHtR

Model I

HR (95% CI)

Model II

HR (95% CI)

Model III

HR (95% CI)

All-cause mortality

  < 0.50

reference

reference

reference

 0.50–0.59

1.745 (1.742, 1.749)

0.772 (0.770, 0.774)

1.004 (1.001, 1.006)

 0.60–0.69

2.645 (2.639, 2.651)

0.840 (0.839, 0.842)

1.123 (1.120, 1.127)

 0.70–0.79

3.356 (3.348, 3.365)

1.190 (1.187, 1.193)

1.591 (1.584, 1.598)

  ≥ 0.80

3.429 (3.418, 3.441)

1.666 (1.660, 1.671)

2.214 (2.200, 2.228)

 P for trend

  

0.007

 Per-0.1 increase

1.410 (1.409, 1.411)

1.175 (1.175, 1.176)

1.368 (1.366, 1.371)

 Per-SD increase

1.410 (1.410, 1.411)

1.175 (1.175, 1.176)

1.369 (1.366, 1.371)

Cardiovascular mortality

  < 0.50

reference

reference

reference

 0.50–0.59

1.225 (1.218, 1.232)

1.501 (1.492, 1.510)

1.534 (1.524, 1.544)

 0.60–0.69

1.541 (1.533, 1.550)

2.015 (2.001, 2.030)

2.045 (2.030, 2.060)

 0.70–0.79

2.790 (2.773, 2.807)

3.470 (3.439, 3.501)

3.518 (3.486, 3.550)

  ≥ 0.80

3.082 (3.059, 3.106)

4.106 (4.054, 4.159)

3.590 (3.545, 3.635)

 P for trend

  

 < 0.001

 Per-0.1 increase

1.594 (1.592, 1.595)

1.403 (1.401, 1.405)

1.437 (1.432, 1.442)

 Per-SD increase

1.594 (1.593, 1.596)

1.403 (1.401, 1.405)

1.437 (1.432, 1.443)

Cancer mortality

  < 0.50

reference

reference

reference

 0.50–0.59

0.756 (0.753, 0.759)

0.931 (0.928, 0.935)

0.960 (0.957, 0.964)

 0.60–0.69

0.720 (0.717, 0.723)

0.878 (0.875, 0.882)

0.932 (0.929, 0.936)

 0.70–0.79

0.773 (0.769, 0.776)

0.887 (0.884, 0.890)

0.972 (0.967, 0.977)

  ≥ 0.80

0.874 (0.868, 0.881)

0.916 (0.909, 0.923)

0.997 (0.989, 1.005)

 P for trend

  

0.130

 Per-0.1 increase

1.275 (1.273, 1.276)

1.012 (1.010, 1.013)

0.998 (0.996, 1.001)

 Per-SD increase

1.275 (1.273, 1.277)

1.012 (1.010, 1.013)

0.998 (0.995, 1.001)

Other-cause mortality

  < 0.50

reference

reference

reference

 0.50–0.59

1.413 (1.409, 1.417)

0.690 (0.688, 0.692)

1.038 (1.034, 1.042)

 0.60–0.69

2.059 (2.053, 2.066)

0.750 (0.748, 0.753)

1.225 (1.219, 1.230)

 0.70–0.79

2.645 (2.636, 2.654)

1.049 (1.045, 1.052)

1.903 (1.891, 1.915)

  ≥ 0.80

3.651 (3.636, 3.667)

1.858 (1.850, 1.866)

3.835 (3.801, 3.869)

 P for trend

  

 < 0.001

 Per-0.1 increase

1.389 (1.388, 1.391)

1.171 (1.170, 1.172)

1.476 (1.472, 1.480)

 Per-SD increase

1.390 (1.389, 1.391)

1.171 (1.170, 1.172)

1.477 (1.472, 1.482)

  1. Model I, unadjusted. Model II, adjusted for age, sex, and ethnicity. Model III, additionally adjusted for BMI education level, marital status, poverty income ratio, smoking status, alcohol consumption, systolic blood pressure, heart rate, ASCVD Diabetes mellitus, COPD Cancer, aspirin, lipid-lowering drugs, hypoglycemic drugs, and laboratory measurements (white blood cell count, hemoglobin, albumin, creatinine, urea nitrogen, glycohemoglobin, total cholesterol, and HDL-C) based on model II. WHtR Waist-to-height ratio. ASCVD Atherosclerotic cardiovascular disease. COPD Chronic obstructive pulmonary disease. HDL-C High-density lipoprotein cholesterol. HR Hazard ratio. CI Confidence interval