Table 2 Hazard Ratios for Alcohol-Attributable Disease Categories in 12,300,516 Men (French National Hospital Discharge database 2008–2012)
Alcohol-Attributable Disease Category | Total, n (%) | AUDs, n (%) | Mean (SD) age at incidence | Hazard Ratio with AUDs (95% CI) | |
|---|---|---|---|---|---|
AUDs | No AUDs | ||||
Liver diseases | |||||
Cirrhosis | 357,809 (2.91) | 155,000 (43.3) | 59.6 (12.0) | 64.9 (16.6) | 15.97 (15.86–16.09) |
Liver cancer | 56,162 (0.46) | 26,199 (46.7) | 65.3 (9.9) | 69.6 (12.4) | 16.12 (15.84–16.40) |
Pancreatic diseases | |||||
Acute pancreatitis | 80,860 (0.66) | 32,711 (40.5) | 48.8 (13.2) | 60.7 (18.0) | 12.14 (11.96–12.32) |
Chronic pancreatitis | 57,465 (0.47) | 31,602 (55.0) | 53.2 (12.3) | 62.3 (16.1) | 20.36 (20.01–20.71) |
Pancreatic cancer | 41,853 (0.34) | 3659 (8.7) | 62.2 (10.9) | 68.6 (12.0) | 1.61 (1.56–1.67) |
Upper aerodigestive tract cancers | |||||
Head and neck cancer | 82,852 (0.67) | 19,875 (24.0) | 57.8 (8.7) | 63.2 (11.9) | 4.39 (4.31–4.46) |
Larynx cancer | 37,952 (0.31) | 8399 (22.1) | 59.0 (8.9) | 64.9 (11.1) | 4.03 (3.93–4.14) |
Oesophageal cancer | 36,083 (0.29) | 6084 (16.9) | 60.7 (9.4) | 66.8 (11.5) | 3.19 (3.10–3.28) |
Colorectal cancer | 190,593 (1.55) | 10,427 (5.5) | 65.7 (10.3) | 69.5 (12.2) | 1.14 (1.11–1.16) |
Cardiovascular diseases | |||||
Ischemic heart disease | 1,290,533 (10.49) | 71,137 (5.5) | 62.6 (11.5) | 68.8 (12.8) | 1.11 (1.10–1.12) |
Congestive heart failure | 980,140 (8.0) | 76,602 (7.8) | 64.4 (12.1) | 73.4 (12.8) | 1.95 (1.94–1.97) |
Atrial fibrillation | 898,455 (7.30) | 54,639 (6.1) | 67.5 (11.5) | 74.4 (11.9) | 1.64 (1.63–1.66) |
Ischemic stroke | 432,393 (3.52) | 34,288 (7.9) | 63.8 (11.4) | 71.3 (13.0) | 1.75 (1.73–1.77) |
Haemorrhagic and other non-ischemic stroke | 108,219 (0.88) | 12,164 (11.2) | 59.6 (12.7) | 67.9 (16.9) | 2.23 (2.19–2.28) |
Dementia | 389,687 (3.17) | 47,349 (12.2) | 65.6 (13.2) | 80.5 (9.1) | 4.67 (4.63–4.72) |
Infectious diseases | |||||
Pneumococcal pneumonia | 28,569 (0.23) | 4799 (16.8) | 56.4 (12.9) | 64.7 (18.6) | 3.71 (3.60–3.83) |
Tuberculosis | 42,945 (0.35) | 4524 (10.5) | 57.4 (13.3) | 61.8 (20.3) | 2.22 (2.15–2.29) |
Injuries | |||||
Non-intentional injury | 357,461 (2.91) | 42,425 (11.9) | 56.7 (15.6) | 56.5 (24.1) | 3.11 (3.08–3.15) |
Self-harm | 144,723 (1.18) | 36,548 (25.3) | 43.1 (12.0) | 39.4 (17.1) | 6.55 (6.47–6.64) |
Other intentional injury | 32,113 (0.26) | 5966 (18.6) | 43.7 (21.9) | 36.7 (18.3) | 5.02 (4.88–5.17) |