Time point | Enrolment | Baseline assessment | Allocation | +16Â weeks assessment | +24Â weeks assessment |
---|---|---|---|---|---|
t-1 | t0 | Â | t1 | t2 | |
Preliminary data: | |||||
 Eligibility screen | ✔ |  |  |  |  |
 Informed consent | ✔ |  |  |  |  |
 Allocation |  |  | ✔ |  |  |
Anthropometric measurements | |||||
 Body mass |  | ✔ |  | ✔ | ✔ |
 Height |  | ✔ |  | ✔ | ✔ |
 Body mass index |  | ✔ |  | ✔ | ✔ |
 Waist circumference |  | ✔ |  | ✔ | ✔ |
 Hip circumference |  | ✔ |  | ✔ | ✔ |
Blood sampling and biochemical measurements | |||||
 Lipid profile (TG, TC, HDLc, LDLc) |  | ✔ |  | ✔ | ✔ |
 Plasma glucose |  | ✔ |  | ✔ | ✔ |
 Plasma glycated haemoglobin |  | ✔ |  | ✔ | ✔ |
 Plasma adiponectin |  | ✔ |  | ✔ | ✔ |
 Plasma Interleucin-6 |  | ✔ |  | ✔ | ✔ |
 Plasma metabolome-lipidome |  | ✔ |  | ✔ | ✔ |
 Plasma MicroRNA |  | ✔ |  | ✔ | ✔ |
Medical procedures | |||||
 Resting blood pressure |  | ✔ |  | ✔ | ✔ |
 Cardiorespiratory fitness (VO2peak) |  | ✔ |  | ✔ | ✔ |
Physical activity and sedentary behaviour | |||||
 Physical activity (LPA and MVPA) |  | ✔ |  | ✔ | ✔ |
 Sedentary time |  | ✔ |  | ✔ | ✔ |
Self-reported Questionnaires | |||||
 Food frequency questionnaire |  | ✔ |  | ✔ | ✔ |
 Healthy eating index |  | ✔ |  | ✔ | ✔ |
 Empowerment related to health |  | ✔ |  | ✔ | ✔ |
 Physical activity and dietary habits self-efficacy |  | ✔ |  | ✔ | ✔ |
 Health related quality of life (EQ-5D) |  | ✔ |  | ✔ | ✔ |
 Direct costs |  |  |  | ✔ |  |
 Indirect costs |  |  |  | ✔ |  |
 Demographic variables |  | ✔ |  |  |  |
 Enjoyment with the programme |  |  |  | ✔ |  |
 Reasons for abandoning |  | ✔ |  | ✔ | ✔ |