The burden of chronic diseases and cost-of-care in subjects with HIV infection in a Health District of Northern Italy over a 12-year period compared to that of the general population

Table 3 Prevalence of chronic diseases in HIV population according to 3-year-time periods

Chronic diseases		2003–2005	2006–2008	2009–2011	2012–2014	Trend	Annual mean change^a	p-value
Subjects observed in the period (n)		2846	3211	3604	3855
Cardio-Cerebrovascular diseases	(n)	387	511	614	798	≈	+0.1 %	NS
Cardio-Cerebrovascular diseases	Prevalence (%)	13.6	15.9	17.0	20.7	≈	+0.1 %	NS
Liver diseases	(n)	573	640	547	428	↓	−4.8 %	<0.001
Liver diseases	Prevalence (%)	20.1	19.9	15.2	11.1	↓	−4.8 %	<0.001
Dyslipidemia	(n)	107	198	263	340	↑↑	+5.5 %	<0.001
Dyslipidemia	Prevalence (%)	3.8	6.2	7.3	8.8	↑↑	+5.5 %	<0.001
Diabetes	(n)	100	149	198	248	↑	+1.6 %	0.042
Diabetes	Prevalence (%)	3.5	4.6	5.5	6.4	↑	+1.6 %	0.042
Cancer	(n)	158	182	232	242	≈	+0.1 %	NS
Cancer	Prevalence (%)	5.6	5.7	6.4	6.3	≈	+0.1 %	NS
Gastrointestinal diseases	(n)	75	95	130	206	↑↑	+5.7 %	<0.001
Gastrointestinal diseases	Prevalence (%)	2.6	3.0	3.6	5.3	↑↑	+5.7 %	<0.001
Neuropathies	(n)	110	136	146	166	≈	+0.2 %	NS
Neuropathies	Prevalence (%)	3.9	4.2	4.1	4.3	≈	+0.2 %	NS
Severe psychiatric disorders	(n)	96	118	141	129	≈	+1.1 %	NS
Severe psychiatric disorders	Prevalence (%)	3.4	3.7	3.9	3.3	≈	+1.1 %	NS
Chronic respiratory diseases	(n)	129	135	122	154	↓↓	−5.6 %	<0.001
Chronic respiratory diseases	Prevalence (%)	4.5	4.2	3.4	4.0	↓↓	−5.6 %	<0.001
Kidney failure	(n)	27	29	41	54	≈	+2.2 %	NS
Kidney failure	Prevalence (%)	0.9	0.9	1.1	1.4	≈	+2.2 %	NS
At least one chronic disease	(n)	966	1096	1150	1148	↓	−0.7 %	0.006
At least one chronic disease	Prevalence (%)	33.9	34.1	31.9	29.8	↓	−0.7 %	0.006

^aAnnual mean change was calculated using multivariate Poisson regression models adjusted for age and gender with in offset the logarithm of general population. NS p > 0.05

ISSN: 1471-2458