Quality assessment | № of participants | Effect | Quality | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Outcome (follow up period) | № of studies | Study design | Risk of biasa | Inconsistencyb | Indirectnessc | Imprecision | Publication or reporting bias | School-based sexual health education | Nothing or usual curriculum | Relative (95 % CI) | Absolute (95 % CI) | |
Herpes Simplex Virus- 2 (54 months) | 3 | randomised trials | not serious | not serious | not serious | not seriousd | none | 746/6146 (12.1 %) | 738/6127 (12.0 %) | OR 1.07 (0.94 to 1.23) | 7 more per 1,000 (from 6 fewer to 24 more) | ⨁⨁⨁⨁ HIGH |
*Condom use (less than six months) | 4 | randomised trials | not serious | not serious | not serious | seriouse | none | 332/741 (44.8 %) | 295/720 (41.0 %) | OR 1.62 (1.03 to 2.55) | 120 more per 1,000 (from 7 more to 229 more) | ⨁⨁⨁◯ MODERATE |
*Condom use (less than six months) | 4 | quasi-experimental trials | not serious | not serious | not serious | Seriousf | None | 90/226 (39.8 %) | 63/197 (32.0 %) | OR 2.88 (1.41 to 5.90) | 255 more per 1,000 (from 79 more to 415 more) | ⨁⨁◯◯ LOW |
*Condom use (six to 10 months) | 6 | randomised trials | not serious | not serious | not serious | not seriousg | none | 485/1238 (39.2 %) | 494/1494 (33.1 %) | OR 1.40 (1.16 to 1.68) | 78 more per 1,000 (from 34 more to 123 more) | ⨁⨁⨁⨁ HIGH |
Condom use (six to 10 months | 2 | quasi-experimental trials | not serious | not serious | not serious | serioush | publication bias strongly suspectedi | 62/146 (42.5 %) | 55/131 (42.0 %) | OR 1.05 (0.65 to 1.71) | 12 more per 1,000 (from 100 fewer to 133 more) | ⨁◯◯◯ VERY LOW |
*Condom use (more than 10 months) | 7 | randomised trials | not serious | not serious | not serious | not seriousj | none | 2955/8106 (36.5 %) | 2678/8868 (30.2 %) | OR 1.22 (0.99 to 1.50) | 43 more per 1,000 (from 2 fewer to 92 more) | ⨁⨁⨁⨁ HIGH |
Condom use (more than 10 months) | 4 | quasi-experimental trials | not serious | not serious | not serious | Seriousk | none | 1442/2205 (65.4 %) | 1647/2649 (62.2 %) | OR 1.18 (0.92 to 1.52) | 38 more per 1,000 (from 20 fewer to 92 more) | ⨁◯◯◯ VERY LOW |