Outcomes/analysis | Combined | Booklet | NC | Total | Combined vs. NC | Booklet vs. NC | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
mean | SD | mean | SD | mean | SD | mean | SD | MD | 95 % CI | p | MD | 95 % CI | p | |
Main analysisa | ||||||||||||||
PHI | 3.0 | 3.6 | 2.0 | 2.9 | 4.5 | 3.8 | 3.1 | 3.6 | -1.5 | -2.8 – -0.3 | 0.01 | -2.5 | -3.8 – -1.3 | 0.00 |
LBP | 21 | 22 | 20 | 20 | 23 | 19 | 21 | 20 | -2 | -9 – 6 | 0.86 | -3 | -11 – 4 | 0.51 |
SA first year | 12 | 22 | 12 | 18 | 16 | 30 | 13 | 24 | -5 | -13 – 4 | 0.39 | -4 | -13 – 4 | 0.56 |
SA second year | 16 | 38 | 12 | 34 | 16 | 23 | 15 | 32 | 0 | -12 – 11 | 1.00 | -4 | -15 – 8 | 0.74 |
SA total in two years | 27 | 50 | 24 | 48 | 32 | 43 | 28 | 47 | -5 | -22 – 12 | 0.76 | -8 | -25 – 9 | 0.50 |
HC costs in 12 months, € | 195 | 700 | 108 | 142 | 303 | 577 | 199 | 530 | -108 | -297 – 82 | 0.37 | -195 | -382 – -7 | 0.04 |
Complete case analysisb | ||||||||||||||
PHI | 2.6 | 3.8 | 1.5 | 3.1 | 4.1 | 4.1 | 2.6 | 3.8 | -1.4 | -3.0 – 0.1 | 0.10 | -2.6 | -4.2 – -0.9 | 0.00 |
LBP | 20 | 23 | 17 | 22 | 23 | 22 | 20 | 22 | -2 | -12 – 8 | 0.87 | -5 | -15 – 4 | 0.41 |
SA first year | 13 | 25 | 12 | 19 | 13 | 20 | 13 | 22 | 0 | -10 – 10 | 1.00 | -2 | -11 – 8 | 0.93 |
SA second year | 16 | 42 | 13 | 39 | 17 | 23 | 15 | 37 | -1 | -17 – 15 | 0.99 | -4 | -20 – 12 | 0.84 |
SA two years | 29 | 55 | 25 | 54 | 30 | 32 | 28 | 49 | -1 | -23 – 21 | 0.99 | -5 | -27 – 16 | 0.83 |
HC costs in 12 months, € | 188 | 808 | 73 | 151 | 370 | 730 | 196 | 633 | -182 | -457 – 93 | 0.26 | -297 | -572 – -22 | 0.03 |