Skip to main content

Table 6 Concurrent validation of 10/66 Dementia and DSM-IV dementia diagnoses

From: The 10/66 Dementia Research Group's fully operationalised DSM-IV dementia computerized diagnostic algorithm, compared with the 10/66 dementia algorithm and a clinician diagnosis: a population validation study

  

Group 1 (n = 2587) Non-cases

Group 2 (n = 134) 10/66 cases not confirmed by DSM-IV

Group 3 (n = 188) DSM-IV cases

Mean difference (group 2 vs group 1)

Mean difference (group 2 vs group 3)

CSI'D' COGSCORE (cognitive test score)

Mean (95% CI)

30.6 (30.5–30.6)

22.4 (21.3–23.7)

17.1 (15.9–18.3)

-8.1 (-6.9 to -9.3)

5.4 (3.7 to 7.1)

 

Median (IQR)

31.0 (29.6–32.1)

23.9 (20.7–27.2)

16.6 (12.3–23.4)

  

CSI'D'RELSCORE(informant reports of cognitive and functional decline)

Mean (95% CI)

1.1 (1.0–1.2)

8.3 (7.3–9.3)

15.4 (14.5–16.3)

7.2 (6.2 to 8.2)

-7.1 (-5.8 to -8.5)

 

Median (IQR)

0.5 (0.0–1.5)

7.5 (5.5–10.0)

14.3 (10.0–20.0)

  

NPI-Q Severity (severity of behavioural and psychological symptoms)

Mean (95% CI)

2.0 (1.9–2.1)

5.0 (4.1–5.9)

7.1 (6.3–7.9)

3.0 (2.2 to 3.9)

-2.1 (-0.9 to -3.2)

 

Median (IQR)

1 (0–3)

3 (1–8)

7 (2–11)

  

NPI'Q' Distress (distress caused to the caregiver by BPSD)

Mean (95% CI)

1.7 (1.6–1.9)

5.0 (3.9–6.1)

7.3 (6.3–8.4)

3.3 (2.2 to 4.3)

-2.3 (-0.8 to -3.8)

 

Median (IQR)

0 (0–2)

3 (0–7)

5 (1–12)

  

WHODAS II Disability

Mean (95% CI)

9.6 (9.1–10.2)

36.0 (30.8–41.2)

48.7 (44.0–53.3)

26.4 (21.2 to 31.6)

-12.7 (-5.7 to -19.7)

 

Median (IQR)

2.8 (0.0–13.9)

26.4 (8.3–63.2)

50.0 (19.4–77.8)

  

Needs for care

No care needed

96.6%

58.7%

29.8%

Chi sq = 1043, 1 df, p < 0.001

 

Needs care some of the time

1.9%

11.6%

15.2%

  
 

Needs care much of the time

1.4%

29.8%

55.1%