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Table 3 Logistic regressions of random effect for MHT treatment in menopause outpatient visits

From: Changes of the prescription of hormone therapy in menopausal women: An observational study in Taiwan

 

Outpatient visits (% prescribing MHT)

Model 1 – no interaction

Model 2 – interaction of WHI and woman education

Model 3 – interaction of WHI and hospital level

 

n

%a

Odds Ratio (95% CI)

Odds Ratio (95% CI)

Odds Ratio (95% CI)

WHI report announcement

     

   After

1157

72.95

0.36 (0.25–0.52)

  

   Before (reference group)

1392

82.97

   

Medical care institution

     

   Metropolitan hospital

627

82.93

14.87 (7.28–30.37)

11.98 (5.82–24.68)

7.02 (3.23–15.27)

   Local community hospital

492

81.10

17.00 (7.92–36.49)

12.09 (5.81–25.14)

12.13 (4.84–30.41)

   Physician clinic

955

83.87

26.42 (13.34–52.32)

16.52 (8.43–32.39)

18.22 (8.12–40.89)

   Ref: Academic medical center

475

58.74

   

WHI on Medical care institution b

     

   WHI effect on metropolitan hospital

    

6.25 (2.08–18.72)

   WHI effect on local community hospital

    

1.69 (0.52–5.49)

   WHI effect on physician clinic

    

2.13 (0.76–5.98)

   WHI effect on academic medical center

    

0.15 (0.34–0.63)

Physician specialty

     

   Obstetrician or gynecologist

1295

85.10

5.34 (3.45–8.26)

6.26 (3.92–10.00)

5.56 (3.60–8.58)

   Ref: other specialty

1254

71.53

   

Demographic factors

     

   Age

  

0.73 (0.41–1.32)

0.72 (0.37–1.40)

0.66 (0.36–1.20)

55–65

719

75.52

   

65+

348

83.62

2.33 (0.81–6.69)

2.43 (0.86–6.92)

4.38 (1.41–13.54)

Ref: 45–55+

1482

78.61

   

   Education

     

Senior high school

373

75.87

0.53 (0.21–1.35)

0.33 (0.09–1.21)

2.46 (1.02–5.93)

Junior high school

446

78.03

0.54 (0.19–1.55)

0.38 (0.11–1.31)

3.11 (1.19–8.10)

Elementary school or lower

1180

80.76

0.95 (0.41–2.19)

0.62 (0.22–1.80)

4.50 (1.83–11.04)

No

322

79.19

1.18 (0.43–3.20)

1.10 (0.31–3.84)

4.90 (1.75–13.72)

Ref: Undergraduate or graduate

228

70.18

   

WHI effect on woman education c

     

   WHI effect on women with senior high school

   

1.64 (0.43–6.22)

 

   WHI effect on women with junior high school

   

1.10 (0.29–4.16)

 

   WHI effect on women with elementary school or lower

   

1.28 (0.40–4.08)

 

   WHI effect on women with no education

   

0.85 (0.20–3.53)

 

   WHI effect on women with undergraduate or graduate

   

0.30 (0.11–0.83)

 

Marital status

     

   Married

2141

77.11

1.03 (0.51–2.10)

0.64 (0.34–1.22)

1.18 (0.62–2.23)

   Ref: Unmarried

408

85.29

   

Economic factors

     

   Employment status

     

Employed

841

79.31

0.94 (0.45–1.94)

0.37 (0.17–0.76)*

0.63 (0.30–1.30)

Ref: Unemployed

1708

77.99

   

Personal income (NT $)

     

<4,999

293

78.16

0.73 (0.31–1.72)

0.66 (0.28–1.59)

0.76 (0.31–1.89)

5,000~19,999

562

79.89

0.72 (0.30–1.71)

0.36 (0.28–1.59)

0.74 (0.32–1.73)

20,000~39,999

431

79.35

1.20 (0.57–2.55)

0.39 (0.18–0.85)

1.14 (0.53–2.45)

>= 40,000

259

71.43

0.24 (0.09–0.59)

0.33 (0.13–0.85)

0.86 (0.31–2.39)

Ref: None

993

79.15

   

Health Status

     

   Illness in the past six months

     

Yes

2188

78.11

1.08 (0.49–2.39)

2.18 (1.07–4.47)

0.81 (0.38–1.73)

Ref: No

361

80.33

   

   Osteoporosis

     

Yes

741

80.43

1.63 (0.91–2.89)

1.48 (0.84–2.59)

1.37 (0.80–2.33)

Ref: No

1808

77.60

   
  1. %a: Percentages in the second column of table 3 were the proportion of outpatient visits with a prescription of MHT in each category. For example, among the 1,157 outpatient visits after the publication of WHI report, there're 72.95% (844 visits) with a prescription of MHT.
  2. WHI and Medical care institutionb: A linear function of the coefficient was estimated and tested in Model 3 with the interaction terms. In order to simplify interpretation, we showed the effect of publication of the WHI on the four types of hospital instead of the interaction terms.
  3. WHI effect and woman educationc: A linear function of the coefficient was estimated and tested in Model 2 with the interaction terms. In order to simplify interpretation, we showed the effect of publication of the WHI on the five categories of level of women education instead of the interaction terms.