From: Ferritin levels and risk of metabolic syndrome: meta-analysis of observational studies
Subgroup | Number of studies | Odds ratio (95% CI) | I 2 | P-value |
---|---|---|---|---|
Study design | ||||
Prospective cohort | 2 | 1.59 (1.38, 1.82) | 0% | |
Cross-sectional | 12 | 1.78 (1.51, 2.09) | 81% | |
Case–control study | 1 | 1.65( 1.43, 1.91) | 0% | 0.551 |
Measure of association | ||||
Odds Ratio | 13 | 1.62 (1.47, 1.79) | 47% | |
Hazard Ratio | 2 | 1.61 (1.49, 1.75) | 37% | 0.520 |
Geographic area | ||||
Asian | 9 | 1.67 (1.38, 2.02) | 84% | |
Europe | 4 | 1.66 (1.50, 1.83) | 14% | |
American | 2 | 2.41 (1.77, 3.27) | 11% | 0.239 |
Adjusted for CRP | ||||
Yes | 9 | 1.92 (1.61, 2.30) | 78% | |
No | 6 | 1.52 (1.36, 1.69) | 41% | 0.044 |
Quality of SCORE statement | ||||
<30 points | 4 | 1.43 (1.27, 1.61) | 0% | |
≥30 points | 11 | 1.87 (1.62, 2.17) | 79% | 0.038 |
Ferritin assay | ||||
RIA | 5 | 1.93 (1.49, 2.51) | 85% | |
TIA | 2 | 1.53 (1.08, 2.16) | 64% | |
Others | 6 | 1.56 (1.42, 1.70) | 17% | 0.091 |
Study size, population | ||||
<300 | 4 | 1.76 (1.512, 2.06) | 57% | |
≥300 | 11 | 1.70 (1.46, 1.98) | 78% | 0.152 |