From: Off-label medicine use in children and adolescents: results of a population-based study in Germany
Drug use categories | Origin of medicines (n = 12,587*) | ||||||||
---|---|---|---|---|---|---|---|---|---|
Prescribed | OTC | Other sources | |||||||
n | % | 95% CI | n | % | 95% CI | n | % | 95% CI | |
Off-label medicine use | 2,344 | 29.9 | (28.9-30.9) | 925 | 30.3 | (28.7-31.9) | 515 | 30.6 | (28.5-32.9) |
➢ Indication | 376 | 4.8 | (4.3-5.2) | 106 | 3.5 | (2.9-4.2) | 56 | 3.3 | (2.6-4.3) |
➢ Age | 326 | 4.2 | (3.7-4.6) | 100 | 3.3 | (2.7-4.0) | 45 | 2.7 | (2.0-3.6) |
➢ Under-dosing | 1,263 | 16.1 | (15.3-16.9) | 590 | 19.3 | (18.0-20.8) | 339 | 20.2 | (18.3-22.2) |
➢ Over-dosing | 379 | 4.8 | (4.4-5.3) | 129 | 4.2 | (3.6-5.0) | 75 | 4.5 | (3.6-5.6) |
In-label medicine use | 5,508 | 70.1 | (69.1-71.1) | 2,129 | 69.7 | (68.1-71.3) | 1,166 | 69.4 | (67.1-71.5) |