Table 1 Articles related to interventions for reducing neonatal mortality from neonatal tetanus

1.

Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes (Review)

The Cochrane Collaboration and published in The Cochrane Library

Systematic review (Cochrane)

India, Bangladesh, Pakistan, Gambia, Nepal, Indonesia

Significant reduction was observed in maternal morbidity, neonatal mortality, stillbirths and perinatal mortality as a consequence of implementation of community-based care packages.

Review included 18 cluster-randomized/quasi-randomized trials

2010, Issue 11

2.

Tetanus toxoid immunization to reduce mortality from neonatal tetanus

International Journal of Epidemiology 2010

Systematic review

India, Columbia

Immunization of pregnant women or women of childbearing age with at least two doses of tetanus toxoid was estimated to reduce mortality from neonatal tetanus by 94%.

3.

Process of neonatal tetanus elimination in Nepal

Journal of Public Health 2009

Cross sectional survey

Nepal

National tetanus toxoid supplemental immunization activities in 2000–2004, raised the proportion of children protected at birth against tetanus to above 80%.

4.

Intra- and inter-household differences in antenatal care, delivery practices and postnatal care between last neonatal deaths and last surviving children in a peri-urban area of India

J. Biosoc. Sci.2010

Comparative cross sectional

India

Higher percentage of tetanus toxoid immunization, safer delivery practices, postnatal care, higher maternal age and greater birth spacing were likely to reduce neonatal mortality.

5.

Maternal and neonatal tetanus

The Lancet 2007

Review paper

India, New Guinea, Columbia, Pakistan

The proposed packages of interventions include improved antenatal care, tetanus toxoid immunization of mothers, and promotion of hygienic delivery and postpartum cord-care, all of which will directly contribute to prevention of maternal and neonatal tetanus.