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Table 3 Demographic, health, and health care use characteristics of COX-2 switchers and COX-2 stoppers in the first 100 days after discrediting of rofecoxib

From: An observational study of the discrediting of COX-2 NSAIDs in Australia: Vioxx or class effect?

Characteristic

COX-2 Switchersa(N = 189)

%

COX-2 Stoppersa

(N = 81)

%

χ2, df, p-value

Continuous Rofecoxib User

47

14

61.90, 1, < 0.0001

Urban Area

57

45

7.54, 1, 0.01

Able to Manage on Income

80

78

0.47, 1, 0.49

No Formal Education

72

73

0.03, 1, 0.87

Marital

Married/De facto

40

36

 
 

Sep/Divorced

4

6

2.29, 1, 0.32

 

Widowed/Single

56

58

 

BMI

Underweight

1

3

 
 

Normal

44

48

0.02b

 

O/weight

55

49

 

Alcohol

Non-drinker

63

68

 
 

Rarely/Low drinker

32

31

0.05b

 

Risky/High Risk

5

1

 

Smoker

4

5

0.77, 1, 0.38

Excellent/Very Good/Good General Health

63

59

0.60, 1, 0.44

Consulted Family Doctor ≥5 Visits

70

79

5.15, 1, 0.02

Hospital Doctor Visit in 12 months

19

26

3.36, 1, 0.07

Specialist Doctor Visit in 12 months

55

62

2.56, 1, 0.11

Conditions:

   

Ever Reported Arthritis

86

77

9.03, 1, 0.003

Hypertension

61

54

2.93, 1, 0.09

Depression

6

8

1.29, 1, 0.26

Anxiety/nervous

7

7

0.15, 1, 0.70

Asthma

9

11

0.24, 1, 0.62

Diabetes

14

11

0.93, 1, 0.33

Bronchitis/Emphysema

5

9

3.3, 1, 0.07

Heart Disease

21

27

2.16, 1, 0.14

Cancer

4

6

1.97, 1, 0.16

  1. a In the first 100 days after rofecoxib discrediting
  2. b Fisher's exact test used due to small cell sizes, p-value only reported