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Table 1 Epidemiologic and Program Data for Zambia

From: Cost-effectiveness of novel vaccines for tuberculosis control: a decision analysis study

Variable

Value

Source

Population (2005)

11,478,000

[56]

Live births/1,000 population (2007)

40.78

[57]

Live births per year

468,073

Calculated from [56, 57]

Percent of global BCG vaccine coverage

0.398%

[34]

Percent of target population vaccinated with BCG

92%

[34]

Gross National Income per capita (US$) 2005

$500

[58]

Life expectancy at birth (years)

38.4

[58]

All cause mortality

Age specific

[59]

New estimated TB smear-positive incidence per 100,000 (2005)

247

[1]

Annual risk of TB infection (ARI)

4.94%

Calculated from [1, 16]

Probability of being diagnosed and treated for LTBI

1%

[20]*

Completion of LTBI treatment

67%

[21]

HIV prevalence (2006)

9.4%

[10]

HIV incidence per annum

0.96%

Calculated from [22]

DOTS coverage (2005)

100%

[1]

DOTS case detection rate (2005)

52%

[1]

Initial drug resistance

  

   Single drug resistance

8.5%

[60]

   Multi drug resistance†

1.8%

[61]

DOTS new case treatment outcomes (2005)

 

[1]

   Cure/complete

83%

 

   Default/transfer/not evaluated

8%

 

   Die

8%

 

   Fail

1%

 

DOTS re-treatment outcomes (2005)

 

[1]

   Cure/complete

78%

 

   Default/transfer/not evaluated

7%

 

   Die

13%

 

   Fail

2%

 
  1. *This assumes only dually infected individuals (HIV and TB) whose HIV infection is detected and are tuberculin tested will be treated (based on a Haitian study)
  2. †Defined as resistance to isoniazid and rifampin, with or without other drug resistance