Parameters | Control group | Intervention group | P value b | |||||
---|---|---|---|---|---|---|---|---|
 | Baseline a (n = 131) | 1-year (n = 131) | 3-year (n = 110) | Baseline (n = 123) | 1-year (n = 123) | 3-year (n = 103) | at 1-year mark | at 3-year mark |
Energy intake (kcal) | 2455 ± 838 | 2292 ± 739* | 2153 ± 734* | 2299 ± 788 | 2097 ± 895* | 2016 ± 677* | 0.647 | 0.794 |
   Fat c (%) | 27.5 ± 5.2 | 27.4 ± 5.2 | 27.8 ± 5.4 | 26.5 ± 5.6 | 25.5 ± 5.6* | 25.7 ± 5.2 | 0.088 | 0.110 |
   Alcohol (g) | 21.0 ± 36.1 | 18.6 ± 29.2 | 13.7 ± 23.2* | 20.1 ± 44.8 | 24.6 ± 87.7 | 15.7 ± 29.8 | 0.171 | 0.149 |
Leisure time physical activity (kcal) | 136 ± 159 | 163 ± 172* | 181 ± 201* | 91 ± 132 | 155 ± 180* | 161 ± 215* | 0.078 | 0.214 |
   Exercise (kcal) | 57 ± 79 | 86 ± 99* | 92 ± 105* | 43 ± 88 | 82 ± 122* | 74 ± 117* | 0.474 | 0.958 |
   Exercise (minutes per week) | 118 ± 160 | 184 ± 206* | 185 ± 229* | 91 ± 187 | 184 ± 262* | 160 ± 229* | 0.339 | 0.556 |
   Non-exercise (kcal) d | 79 ± 139 | 76 ± 133 | 90 ± 174 | 49 ± 85 | 74 ± 119* | 88 ± 186* | 0.045 | 0.148 |
Weight (kg) | 63.9 ± 11.7 | 63.1 ± 11.7* | 62.5 ± 11.2* | 64.9 ± 12.9 | 63.5 ± 12.9* | 63.1 ± 12.9* | 0.023 | 0.069 |
Body mass index (kg/m2) | 24.5 ± 3.2 | 24.2 ± 3.1* | 24.4 ± 3.3* | 24.8 ± 3.6 | 24.2 ± 3.6* | 24.3 ± 3.7* | 0.022 | 0.051 |
Waist circumference (cm) | 84.4 ± 9.4 | 83.3 ± 8.6* | 84.2 ± 9.5 | 85.9 ± 10.9 | 84.2 ± 10.5* | 84.7 ± 11.9 | 0.309 | 0.362 |
Fasting plasma glucose (mmol/l) | 6.1 ± 0.5 | 5.9 ± 0.6 | 6.0 ± 0.9 | 5.9 ± 0.5 | 5.8 ± 0.6* | 6.0 ± 0.8 | 0.698 | 0.481 |
2-hplasma glucose (mmol/l) | 9.0 ± 0.9 | 8.3 ± 2.0* | 8.5 ± 2.4 | 9.2 ± 0.9 | 8.0 ± 2.1* | 8.4 ± 2.5* | 0.083 | 0.553 |
Fasting insulin (pmol/l) | 43.8 ± 21.6 | 44.4 ± 40.8 | 45.8 ± 23.9 | 43.2 ± 22.2 | 44.4 ± 25.2 | 47.6 ± 36.1 | 0.861 | 0.632 |
2-h insulin (pmol/l) | 330.6 ± 211.8 | 308.4 ± 178.8 | 377.4 ± 280.7 | 337.8 ± 199.8 | 342.0 ± 271.2 | 390.0 ± 374.2 | 0.413 | 0.999 |
Matsuda index e | 5.4 ± 3.5 | 5.6 ± 3.3 | 5.3 ± 3.2 | 4.8 ± 2.3 | 5.9 ± 3.7* | 5.5 ± 3.4* | <0.001 | <0.001 |
Aspartate aminotransferase (IU/l) | 25 ± 8 | 25 ± 12 | 26 ± 15 | 25 ± 12 | 23 ± 13 | 25 ± 17 | 0.170 | 0.977 |
Alanine aminotranseferase (IU/l) | 25 ± 16 | 26 ± 17 | 27 ± 16 | 26 ± 18 | 24 ± 17 | 25 ± 14 | 0.212 | 0.520 |
Gamma-glutamyltransferase (IU/l) | 53 ± 58 | 59 ± 91 | 59 ± 97* | 48 ± 46 | 44 ± 47* | 43 ± 66 | 0.041 | 0.158 |