Table 3 Standardized mortality ratio by cause of death, injecting-drug status and sex in HIV-infected subjects compared with persons in the general population not diagnosed with HIV infection; Navarre, Spain, 1999-2006
From: Mortality by causes in HIV-infected adults: comparison with the general population
Observed deaths | Expected deaths | Standardized mortality ratio | (95% CI) | |
|---|---|---|---|---|
All HIV-infected subjects | ||||
All-cause deaths | 210 | 15.0 | 14.0 | (12.2-16.1) |
Non-AIDS deaths | 104 | 15.0 | 6.9 | (5.7-8.5) |
Liver disease | 36 | 0.5 | 69.0 | (48.1-78.6) |
Non-AIDS defining cancer | 17 | 5.4 | 3.2 | (1.8-5.1) |
Drug overdoses or addiction | 23 | 0.5 | 46.0 | (29.2-69.0) |
Cardiovascular disease | 8 | 2.6 | 3.1 | (1.3-6.1) |
Suicide | 7 | 0.7 | 9.6 | (3.8-19.7) |
Other external causes | 4 | 3.0 | 1.3 | (0.4-3.4) |
All other causes | 9 | 1.8 | 5.1 | (2.3-9.7) |
Injecting drug users | ||||
All-cause deaths | 162 | 9.1 | 17.7 | (15.2-20.8) |
Non-AIDS deaths | 88 | 9.1 | 9.6 | (7.7-12.0) |
Liver disease | 30 | 0.3 | 96.6 | (65.2-138.1) |
Non-AIDS defining cancer | 12 | 3.0 | 4.0 | (2.1-7.0) |
Drug overdoses or addiction | 23 | 0.4 | 63.4 | (40.2-95.1) |
Cardiovascular disease | 6 | 1.5 | 4.0 | (1.5-8.6) |
Suicide | 5 | 0.5 | 10.8 | (3.5-25.3) |
Other external causes | 4 | 2.0 | 2.0 | (0.5-5.1) |
All other causes | 8 | 1.1 | 7.3 | (3.2-14.4) |
Non-injecting drug users | ||||
All-cause deaths | 48 | 5.9 | 8.2 | (6.0-11.0) |
Non-AIDS deaths | 16 | 5.9 | 2.7 | (1.6-4.4) |
Liver disease | 6 | 0.2 | 28.4 | (10.4-62.0) |
Non-AIDS defining cancer | 5 | 2.3 | 2.1 | (0.7-5.0) |
Drug overdoses or addiction | 0 | 0.1 | 0 | |
Cardiovascular disease | 2 | 1.1 | 1.8 | (0.2-6.6) |
Suicide | 2 | 0.3 | 7.4 | (0.89-26.6) |
Other external causes | 0 | 1.0 | 0 | |
All other causes | 1 | 0.7 | 1.5 | (0.04-8.2) |
Male | ||||
All-cause deaths | 162 | 12.5 | 12.9 | (11.0-15.1) |
Non-AIDS deaths | 78 | 12.5 | 6.2 | (4.9-7.9) |
Liver disease | 25 | 0.5 | 54.1 | (35.0-80.1) |
Non-AIDS defining cancer | 13 | 4.1 | 3.1 | (1.7-5.4) |
Drug overdoses or addiction | 20 | 0.5 | 43.3 | (26.5-66.7) |
Cardiovascular disease | 6 | 2.4 | 2.5 | (0.9-5.6) |
Suicide | 4 | 0.5 | 7.3 | (2.0-18.7) |
Other external causes | 3 | 2.7 | 1.1 | (0.2-3.3) |
All other causes | 7 | 1.4 | 5.0 | (2.0-10.2) |
Female | ||||
All-cause deaths | 48 | 2.5 | 19.5 | (14.2-26.1) |
Non-AIDS deaths | 26 | 2.5 | 10.6 | (6.9-15.5) |
Liver disease | 11 | 0.1 | 183.3 | (91.5-328.1) |
Non-AIDS defining cancer | 4 | 1.2 | 3.3 | (0.9-8.3) |
Drug overdoses or addiction | 3 | 0.04 | 78.5 | (16.2-229.3) |
Cardiovascular disease | 2 | 0.2 | 8.0 | (1.0-29.0) |
Suicide | 3 | 0.2 | 16.4 | (3.4-47.8) |
Other external causes | 1 | 0.3 | 2.9 | (0.1-16.4) |
All other causes | 2 | 0.4 | 5.5 | (0.7-20.0) |