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Table 3 Risk of incident cardiovascular disease associated to hypercholesterolemia and hypertension in a cohort of adult population from Murcia (south-east Spain)

From: Cardiovascular risk estimated after 13 years of follow-up in a low-incidence Mediterranean region with high-prevalence of cardiovascular risk factors

 

Ischemic heart disease

Stroke

All events

 

Angina

AMI

All ischemic events

    
 

Py/cases

HR (95%CI)

Py/cases

HR 95%CI

Py/cases

HR 95%CI

Py/cases

HR 95%CI

Py/cases

HR 95%CI

Hypercholesterolemia a

          

No

19194/12

1

19213/10

1

19170/19

1

19288/20

1

19113/37

1

Controlled

2609/5

1,22 (0,39-3,81)

2629/4

1,30 (0,39-4.37)

2606/7

1,18 (0,47-2,96)

2676/7

1,44 (0,56-3,67)

2578/11

1,08 (0,53-2,24)

Uncontrolled

3814/16

2,20 (0.94-5.16)

3813/22

3,57 (1,57-8.12)

3757/29

2,83 (1,49-5,37)

3913/9

1,08 (0,45-2,60)

3724/32

1.89 (1,11-3,23)

     

P heterogneity by sex = 0.789

P heterogneity by sex = 0.097

P heterogneity by sex = 0.217

Hypertension b

         

No

16631/7

1

16633/7

1

16614/12

1

16683/9

1

16580/18

1

Controlled

2043/4

3,32 (0,89-12,36)

2069/2

1,80 (0,36-9,17)

2040/5

2,71 (0,90-8,12)

2126/4

1,98 (0,56-6.98)

2037/7

2,22 (0,89-5,54)

Uncontrolled

7238/23

2,78 (1,10-7,08)

7248/28

4,06 (1,64-10.03)

7172/40

3,15 (1,55-6,40)

7341/24

2,31 (0.98-5,43)

7070/56

2,85 (1,60-5,06)

     

P heterogneity by sex = 0.030

P heterogneity by sex = 0.995

P heterogneity by sex = 0.053

  1. AMI: Acute myocardial infarction; Py: Person-years. HR: Hazard ratio. CI: confidence interval.
  2. aControlled hypercholesterolemia defined as prior diagnosis of hypercholesterolemia or use of lipid-lowering medication and total serum cholesterol <240 mg/dl; uncontrolled hypercholesterolemia defined as total serum cholesterol ≥240 mg/dl.
  3. bControlled hypertension defined as prior diagnosis of hypertension or use of anti-hypertensive medication and systolic/diastolic blood pressure <140/90 mmHg; uncontrolled hypertension defined as systolic/diastolic blood pressure ≥140/90 mmHg.