Table 2 Definitions and criteria used to collect respiratory and cardiovascular risk factors and main comorbidities among cohort members in the CAPAMIS Study.*

History of prior pneumonia

Includes influenza-related pneumonia (J10.0 and J11.0), viral pneumonia (J12), pneumococcal pneumonia (J13), pneumonia due to Haemophillus influenzae (J14), bacterial pneumonia (J15), pneumonia due to other infectious organisms (J16), pneumonia in diseases classified elsewhere (J17) and pneumonia due to unspecified microorganisms (J18).

History of coronary artery disease

Includes angina (I20), acute myocardial infarction (I21), subsequent or recurrent myocardial infarction (I22) and chronic ischaemic heart disease (I25).

History of stroke

Includes haemorrhagic stroke (I60 to I62), cerebral infarction (I63) and stroke not specified as haemorrhage or infarction (I64); it does not include transient ischaemic attacks (code G45).

Hypertension

Defined as the presence of any code I10, I11, I12, I13 or I15.

Hypercholesterolemia

Defined as the presence of code E78.

Diabetes mellitus

Codes E10 to E14.

Obesity

Patients with registered code E66 (BMI>30%).

Smoking

Includes patients with current smoking (code F17 active at study start).

Alcoholism

Includes patients with code F10 active at study start.

History of heart disease

Includes congestive heart failure (I50), hypertensive heart disease (I11), cardiomyopathy (I42), cardiac dilatation or ventricular hypertrophy (I11.9 or I51.7) and coronary artery disease (I20, I21, I22 and I25).

History of vascular ischaemia

Besides coronary artery disease and stroke, it Includes atheroesclerosis (I70), acute arterial embolism or thrombosis (I74) and peripheric arterial disease or intermittent claudication (I73.9).

Chronic pulmonary disease

Includes chronic bronchitis or emphysema (J42 to J44) and asthma: (J45).

Severe liver disease

Includes chronic viral hepatitis (B18), alcoholic hepatitis (K70) and cirrhosis (K74).

Severe nephropathy

Includes nephrotic syndrome (N04 or N39.1), renal failure (N18, N19) and kidney dialysis (Y84.1) or transplantation.

Immunocompromise

Defined as the presence of any immunodeficiency (D80 to D84), AIDS (B20 to B24), anatomic or functional asplenia (D73.0 and Q89.0), cancer, severe nephropaty, or long-term corticosteroid therapy (20 mg/day of prednisone or equivalent).